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Remodeled connexin 43 hemichannels alter cardiac excitability and promote arrhythmias | Journal of
This work demonstrates that the opening of lateralize cardiac connexin-43 hemichannels, in the absence of a cardiac pathology, is still sufficient to alter card
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Identification of an anergic BND cell–derived activated B cell population (BND2) in young-onset type
The role of B cells in T1D remains poorly understood. We identified an activated B cell subset that is enriched in insulin reactivity and increased in the blood
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Phosphoinositide regulation of voltage-gated sodium channels | Journal of General Physiology
JGP study reveals that the membrane lipid PI(4,5)P2 alters the activity of NaV1.4 channels by modulating their gating behavior.
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Centralspindlin proteins Pavarotti and Tumbleweed along with WASH regulate nuclear envelope budding
Nuclear envelope (NE) budding is a nuclear export pathway for large macromolecular machineries. Davidson et al. show that the Centralspindlin proteins Pav and T
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Dietary protein shapes the profile and repertoire of intestinal CD4+ T cells | Journal of
Lockhart et al. demonstrate that exposure to food protein drives an antigen-specific CD4+ T cell response characterized at steady state by accumulation at the i
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Distinct domains in Ndc1 mediate its interaction with the Nup84 complex and the nuclear membrane
Amm et al. define an amphipathic helix in Ndc1, an essential nuclear pore and spindle pole body transmembrane protein, genetically interacting with similar moti