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Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human
IL1RN ( adj = 1.65 × 10 –29) in BG. The top DEGs in each training stimulus compared with nontrained control followed similar patterns in the M-MONO and M-PBMC groups (Figure 2B). Additionally, most si...
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Abstract Periodontal disease, a bacterial infection affecting a large percentage of the world's population, is an important risk factor for several systemic diseases and is significantly worsened by d...
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About the Journal of Clinical Investigation
Open access. All content freely available online from the moment of publication. While all articles are open access, those published in issues prior to January 4, 2022, may require permission for use;...
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Reporting requirements for clinical trials In accordance with Uniform Requirements for Manuscripts Submitted to Biomedical Journals, issued by the International Committee for Medical Journal Editors (...
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Effective with the Janury 4, 2022, issue, JCI is a Gold Open Access journal in which all content is freely available without charge to the user or their institution. Authors retain copyright to their ...