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Linux4Chemistry - Directory of available software for chemistry for Linux platforms
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Non-nucleoside Inhibitors to Fight Drug Resistance
RNase H (red) and NNRTI-binding (cyan) sites are highlighted. Fig. 2 In the DNA polymerization cycle by RT, the primer-grip helps repositioning the 3’-end of the primer after each nucleotide incor...
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Thumb movement-1
Comparison of the structures of HIV-1 RT/NNRTI complexes with unliganded HIV-1 RT showng a large movement of the p66-thumb subdomain caused by the binding of an NNRTI to RT. In the epo-enzyme structu...